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Lecture 20

PHGY 210- Lecture 20- Dr. Guevara.docx

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Department
Physiology
Course Code
PHGY 210
Professor
Ann Wechsler

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Lecture Twenty- Wednesday, February 17 , 2010 th Computer Simulation of Reentry -Circus-movement reentry (see slide) -Spiral-movement reentry: In contrast to circus-movement reentry, no anatomical obsticle needed to generate spiral-wave reentry -see picture in slides Activation wave front= top curve in picture -Difibrillating heart: looks like a “bag of worms”, activation is no longer synchronized and no blood gets pumped Ignore Pulmonary Vein Ablation for Treatment of Atrial Fibrillation slide Receptor (Rianodine receptor) is also a Ca2+ channel. The Cardiac Cycle -Systole: “To draw together, contract” Can be atrial or ventricular systole, but when you see systole by itself, it almost certainly means ventricular systole.  Isovolumetric ventricular contraction o AV valves closed o Aortic and pulmonary valves closed o Atria relaxed, ventricles contract  Ventricular ejection (blood flows out of ventricle) o AV valved closed o Aortic and pulmonary valves open o Atria relaxed, ventricles contract -Diastole: “A putting asunder, separation, expansion, dilation”  Isevolumetric ventricular relaxation o AV valves closed o Aortic and pulmonary vavles closed o Atria relaxed, ventricles relaxed  Ventricular filling (blood flows into ventricles)  happens for a long time o AV valves open
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