PHGY 212 Lecture Notes - Lecture 2: Liver Disease, Lead Poisoning, Fluid Compartments
1 Nov 2016
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Blood laboratory: make lab protocol for each experiment and bring to the lab. List of reagents: one sentence outlining purpose of experiment, step-by-step list of instructions, short recipe, max 1 page per experiment, don"t do for parts not doing, i. e. blood smear, make sure mix blood, wipe down outside pipette. Erythrocyte fragility & osmosis: rbc will hemolyse (rupture) when subjected to osmotic stress, contents released into solution (hemoglobin, water flows from low osmolarity solution to high. Increased levels of plasma fibrinogen & gamma globulins. Von willbrand factor: 15% have are rh- (genotype rh-/rh-) If mother is rh+, doesn"t matter what baby is, it"s not a problem. If mother is rh-, then if baby rh+ then it can be a problem. Low rbc count: anemia --high rbc destruction, low rbc production, blood loss, smaller rbc size, bone marrow disease, iron/vitamin b12/folic acid deficiency, decreased oxygen-carrying capacity, vitamin b12 efficiency: macrocytic (big) & normochromic (normal hb)
