PHGY 313 Lecture Notes - Lecture 11: Adaptive Immune System, Antigen-Presenting Cell, Innate Immune System
24 May 2016
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Document Summary
Phgy 313-lecture 11: organization and structure of the immune system: Ability to resist an infection against a particular pathogen. Local accumulation of fluid, plasma, proteins, and wbc that is initiated by physical injury, infection, or local immune response. Immune system protects against 4 types of pathogens. 2 arms of the immune system: innate vs adaptive. Part of response to infection that"s due to the presence of /and immediate activation of the body"s relatively non-specific defense mechanisms. Antimicrobial barriers, antimicrobial peptides, complement system, and prrs o. Response of antigen-specific lymphocytes to antigen inducing the development of immunological memory o. Immunity to infection caused by an adaptive immune response. Response to an initial infection occurs in 3 phases: o. First two phases (innate immunity) rely on prrs. Immediate = general effectors attack pathogens (antimicrobial peptides, nonspecific) o rearrangements) Later = triggered by prrs, promotion of inflammation, removal of pathogens. Adaptive immunity uses antigen-specific receptors (result of gene segment.
