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Lecture 6

PSYC 211 Lecture 6: 6
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Department
Psychology
Course Code
PSYC 211
Professor
Yogita Chaudasama

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11
Lecture'#6'
Neural'Integration'
- the$interaction$of$the$excitatory$and$inhibitory$synapses$on$a$particular$neuron$$
- if$several$excitatory$synapses$are$active$at$the$same$time,$the$EPSP$will$travel$toward$the$axon$
and$the$axon$will$fire$
o activity$of$the$excitatory$synapses$produces$EPSPs$in$postsynaptic$neuron$
o axon$hillock$reaches$threshold$of$excitation;$action$potential$is$triggered$in$axon$
- if$several$inhibitory$synapses$are$active$at$the$same$time$as$the$EPSP,$the$IPSP$will$diminish$
the$size$of$the$EPSP$and$prevent$the$axon$from$firing$
o activity$of$inhibitory$synapses$produces$IPSPs$in$postsynaptic$neuron$
o IPSPs$counteract$EPSPs,$action$potential$is$not$triggered$in$axon$
Neural.Inhibition.does.always.produce.behavioral.inhibition.
- for$example,$a$group$of$neurons$may$prevent$me$from$putting$my$hand$in$the$fire.$If,$however,$
those$neurons$are$inhibited$(i.e.$prevented$from$producing$an$IPSP),$those$neurons$will$NOT$
suppress$my$behavior$and$I$will$put$my$hand$in$the$fire$
o inhibition$of$inhibitory$neurons$makes$the$behavior$for$likely$
neural.excitation.does.not.always.produce.behavioral.excitation.
- for$example,$when$we$are$dreaming,$a$group$of$inhibitory$neurons$are$activated$to$prevent$us$
from$acting$out$our$dreams.$If$this$activation$fails$to$occur,$people$will$at$out$their$dreams$
o excitation$of$neurons$that$inhibit$a$behavior,$suppresses$that$behavior$
- autoreceptorsà$do$not$control$ion$channels$or$affect$the$membrane$potential$but$regulate$
internal$factors,$inhibitory$and$decreases$the$level$of$neurotransmitter$release$(on$the$post$
synaptic$level)$
- axosymatic$or$axodendritic$(figure$2.38)$
$
Psychopharmacology:'Drugs'and'their'Effectiveness'
What'is'a'drug?'
a. a$chemical$substance$used$in$the$treatment,$cure,$prevention$or$diagnosis$of$disease$or$used$to$
enhance$physical$or$mental$well$being$
b. a$chemical$substance$that$has$“perceived”$beneficial$effects$on$perception,$consciousness,$
personality$and$behavior$(e.g.$narcoticsà$numbing$pain;$opium,$hallucinogens).$Some$drugs$
can$cause$addiction$if$abused$(e.g.$cocaine,$heroin)$

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Description
Lecture #6 Neural Integration - the interaction of the excitatory and inhibitory synapses on a particular neuron - if several excitatory synapses are active at the same time, the EPSP will travel toward the axon and the axon will fire o activity of the excitatory synapses produces EPSPs in postsynaptic neuron o axon hillock reaches threshold of excitation; action potential is triggered in axon - if several inhibitory synapses are active at the same time as the EPSP, the IPSP will diminish the size of the EPSP and prevent the axon from firing o activity of inhibitory synapses produces IPSPs in postsynaptic neuron o IPSPs counteract EPSPs, action potential is not triggered in axon Neural Inhibition does always produce behavioral inhibition - for example, a group of neurons may prevent me from putting my hand in the fire. If, however, those neurons are inhibited (i.e. prevented from producing an IPSP), those neurons will NOT suppress my behavior and I will put my hand in the fire o inhibition of inhibitory neurons makes the behavior for likely neural excitation does not always produce behavioral excitation - for example, when we are dreaming, a group of inhibitory neurons are activated to prevent us from acting out our dreams. If this activation fails to occur, people will at out their dreams o excitation of neurons that inhibit a behavior, suppresses that behavior - autoreceptorsà do not control ion channels or affect the membrane potential but regulate internal factors, inhibitory and decreases the level of neurotransmitter release (on the post synaptic level) - axosymatic or axodendritic (figure 2.38) Psychopharmacology: Drugs and their Effectiveness What is a drug? a. a chemical substance used
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