PSYC 211 Lecture Notes - Lecture 61: Reinforcement, Fetal Alcohol Spectrum Disorder, Dopamine Agonist

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Normal boys waited patiently when a signal was not present. Adhd boys showed intermittent, burst of rapid responses whether the signal was present or not. Methylphenidate, a dopamine agonist, alleviates symptoms of adhd: thus, adhd related to reduced dopaminergic transmission. But, mice with a reduction in dopamine transporters show abnormally high extracellular levels of dopamine in the brain leading to hyperactivity in novel environments (i. e. adhd symptoms), which can be inhibited by amphetamine. Dopamine has a modulatory effect on behavior. Drug addiction involves: repeated consumption of drug (natural or synthetic, an overpowering desire or need (compulsion) to continue taking the drug and obtain it by any means necessary. 123: a tendency to increase the dose, detrimental effects on the individual and society. Drug addicts are habitual drug users who continue to take a drug despite its adverse effects on their health and social life. Addictive drugs stimulate brain mechanisms of reinforcement responsible for positive reinforcement.

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