PSYC 211 Lecture Notes - Lecture 21: Basal Ganglia, Indirect Pathway Of Movement, Balance Disorder
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But, too much dopamine stimulation causes involuntary movements and postures (dyskinesia and dystonia: l-dopa does not work indefinitely; the number of dopamine neurons decline and the symptoms gets worse. Huntingtons chorea: huntington"s chorea is a genetic disorder. It is part of the basal ganglia group of disorders: huntingtons patients show uncontrollable movement, especially jerky limb movements. Sometimes known as huntington"s dance: caused by degeneration of the caudate-putamen which leads to a reduction in the inhibition provided by gaba-secreting neurons of the caudate-putamen. This effects the overall activity of the indirect pathway. The cerebellum and movement skill: the cerebellum is a large and conspicuous part of the motor system, known as the little brain, it has two hemispheres, and a small lobe called the flocculus which. Its outputs project to every major motor structure of the brain projects from its ventral surface. Beta activity is desynchronous; its a reflection of different neural circuits actively proccessing info at the same time.