PSYC 337 Lecture Notes - Lecture 5: Cortisol, Gene-Environment Correlation, Macguffin
31 Jan 2018
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Associated with more biology abnormally and changes in sleep. Higher rate of symptoms in relatives of the patients and worsen over time. Once psychotic, the following episodes might also be psychotic. Patients look ok at pre-morbid functioning & personality. Don"t respond to placebos and less respond to antidepressants. Not stable across episodes, may transform to depression and not meet the criteria for melancholia anymore. Lack of reactivity to good and bad activity. Earlier onset & more comorbidity (e. g. anxiety & borderline personlaity disorder) Still have reactivity to environment and can be greatly affected in mood. Response to very specific treatment [monoamine oxidase inhibitors (maois) & Response to very specific treatment [monoamine oxidase inhibitors (maois) & selective serotonin reuptake inhibitors (ssris)] More sever course and hard to treat, also worsen over time. Respond rapidly to light treatment (but also seen in other depression) Slow onset, often thought to be "how i am" Many impairment in work, academic, interpersonal, not daily bases.
