ANTHROP 2D03 Lecture Notes - Lecture 12: Dna Database, Felony, Genetic Testing
4 Sep 2018
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Lo(cid:272)ard ex(cid:272)ha(cid:374)ge pri(cid:374)(cid:272)iple: (cid:862)a (cid:272)ross tra(cid:374)sfer of e(cid:448)ide(cid:374)(cid:272)e o(cid:272)(cid:272)urs (cid:449)he(cid:374)e(cid:448)er a perso(cid:374) (cid:272)o(cid:373)es i(cid:374)to (cid:272)o(cid:374)ta(cid:272)t (cid:449) a(cid:374) o(cid:271)je(cid:272)t or a perso(cid:374)(cid:863) Implies comparison of things at crime scene and known reference samples get unique identifier. 1980 ray white describe first polymorphic rflp marker. 1985 alec jeffery discover multilocus vntr probes. Short tandem repeats are found in genome (have multiple copies and multiple alleles) Historical investigation nazis, 9/11: missing persons, mass disasters putting pieces back together, military dna dog tag. Determine what or which samples to send through analysis and using which method. Extraction, quantification, amplification and data acquisition using ce. Sensitive and prone to contamination (quantity) quantity over quality. Slightly different methods based on what has happen. Principles of dna typing: do the profiles match, how rare or common is the match (frequency of occurrence, is the match valid and reliable performed properly. Include continue to look @ this ind. Inconclusive contaminated, or not enough markers to do either.
