BIOCHEM 2EE3 Lecture Notes - Lecture 2: Relative Permittivity, Hydrogen Bond, Hydrophile

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Amphipathic molecules in aqueous solution: display both hydrophobic and hydrophilic properties and include fatty acids, detergents and lipids, the head group is typically hydrophilic and readily interacts with water. Module 2 video 2: the nonpolar tail is typically a hydrocarbon chain that is highly hydrophobic and interacts with other hydrophobic chains, amphipathic molecules are building blocks of membranes. =(cid:4666)(cid:883). (cid:882) (cid:883)(cid:882)7(cid:4667) (cid:4666)(cid:883). (cid:882) (cid:883)(cid:882)7(cid:4667)=(cid:883). (cid:882) (cid:883)(cid:882)(cid:2869)(cid:2872: equilibrium constant- ration of concentration of products over reactants for a reaction at equilibrium, k > 1, equilibrium favours product, k < 1, equilibrium favours reactants. Power of hydrogen" or the potential of the hydrogen ion" scale. Inverse relationship so the larger the ka, the stronger the acid, the smaller the pka: (cid:1853)+(cid:1854)=(cid:883)4. The consequences of ph changes in biomolecules: ph and change in p play a huge role on function of biomolecules by changing their overall net charge, ex. human ubiquitin.

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