Class Notes (838,243)
Canada (510,789)
Biochemistry (232)
BIOCHEM 2EE3 (157)
Lecture

E Metabolism.pdf

5 Pages
134 Views
Unlock Document

Department
Biochemistry
Course
BIOCHEM 2EE3
Professor
Boris Zhorov
Semester
Winter

Description
E Metabolism Learning Objectives: • Catabolic and anabolic pathways • Energy flow in metabolism • Overview of catabolism • ATP + high energy compounds • Locations and control of metabolism. Metabolism: Highly integrated cell activity, involving hundreds of enzyme-catalyzed reactions from which biomolecules are produced, maintained and destroyed, and by which energy is obtained and used. • Hundreds of integrated enzyme catalyzed rxns • Maintains, produces and destroys biomolecules • Energy is obtained or used • Some reactions are common to all organisms. Variations in metabolic reactions are mainly due to differences in free energy sources Divided into two parts: 1. Catabolism: Sum of reactions of degradation in which nutrients and self biomolecules are broken down to produce energy and monomers that are necessary for the synthesis of biopolymers 2. Anabolism: Sum of reactions of biosynthesis in which biological molecules are synthesized from smaller components. Living Organisms are divided based on how they obtain free energy and carbon E Metabolism 1. Autotrophs: Use CO fro2 atmosphere as sole source of carbon. Photoautotrophs (plants) obtain energy from sunlight. Chemolithotrophs Obtain free energy through the oxidation of inorganic componunds. 2. Heterotrophs: Obtain carbon and energy from autotrophs. Vitalism: Old doctrine, now rejected, that claims that living organisms are fundamentally different from non-living entities because they contain a non-physical component or are governed by different principles than inanimate objects. Often refers to a driving force, or vital energy that is equated to a soul. Antoine LaVoisier (1743-1794): Father of modern chemistry. • Demonstrated nature of combustion • Proposed the term oxygen. • Developed new system of chemical nomenclature • Wrote first modern text for chemistry • Responsible for agricultural reform, tax collection, and gunpowder manufacture as a government official. Executed during Reign of Terror. Metabolic Pathways: Series of connected metabolic reactions that make a specific product 1. Exergonic Reactions: Catabolic reactions that break down metabolites to release free energy 2. Endergonic Reaction: Anabolic reactions that synthesize simple metabolites to store and invest free energy Metabolites: Reactants, intermediates and products of a metabolic pathway Energy Flow in Metabolism ADP, NAD , NADP , HPO
More Less

Related notes for BIOCHEM 2EE3

Log In


OR

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit