BIOCHEM 2EE3 Lecture 10: Module 6 Video 1
8 Dec 2017
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Document Summary
All scientific fields dealing with cell biology have one central dogma at their core: Dna (the genetic information of life) is transcribed to rna (we will be focusing on mrna), which is translated to a protein. Now we"ve already dealt with the two bookends of this process: dna and its replication and proteins and their folding. Let"s now look into the process that leads from dna to protein. We"re going to initially focus on bacterial transcription as it is a tad simpler than eukaryotic transcription and it does share a lot of the features with eukaryotic transcription. The process itself has 3 phases: phase 1: initiation phase 2: elongation phase 3: termination. The key protein player in transcription is rna polymerase. You have already encountered dna polymerases so you know the main job of this protein. The rna designation tells us that the product will be rna-based not dna-based. The dna sequence itself encodes for a number of key elements:
