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Class Notes for Biochemistry at McMaster University

BIOCHEM 3G03 Lecture Notes - Lecture 2: Relative Permittivity, Liquid Hydrogen, Lipid Bilayer
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Water Molecules and Hydrogen Bonds water is polar and hydrogen bonds form between the oxygen and hydrogen of neighbouring molecules water is highly cohesive - accounts for its surface tension that allows insects to walk on...

Biochemistry
BIOCHEM 3G03
Daniel Yang
BIOCHEM 3G03 Lecture Notes - Lecture 3: Phosphodiester Bond, Complementary Dna, Polynucleotide
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From Genes to Proteins Nucleotides has a nitrogen-containing base adenine, guanine = purines cytosine, thymine = pyrimidines RNA has uracil instead of thymine also contains a phosphate group and 5 membered-ring a nucleosid...

Biochemistry
BIOCHEM 3G03
Daniel Yang
BIOCHEM 3G03 Lecture Notes - Lecture 1: Phosphodiester Bond, Monosaccharide, Cell Nucleus
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Chapter 1 - Chemical Basis of Life Major Biomolecules in Cells 1) Amino Acids: contain an amino (-NH2) and carboxylic acid (-COOH) group ionized to --NH3+ and --COO- under physiological conditions all amino acids have the ...

Biochemistry
BIOCHEM 3G03
Daniel Yang
BIOCHEM 3G03 Lecture Notes - Lecture 6: Enzyme Catalysis, Acetoacetic Acid, Schiff Base
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How Enzymes Work How to increase rate of a chemical reaction: increasing the temperature increasing concentrations of reacting substrates adding a catalyst Chymotrypsin synthesized in pancreas and secreted into small intes...

Biochemistry
BIOCHEM 3G03
Daniel Yang
BIOCHEM 3G03 Lecture Notes - Lecture 5: Myoglobin, Torr, Cooperative Binding
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Chapter 5 - Protein Function Myoglobin and Hemoglobin: Oxygen-Binding Proteins myoglobin is a small protein with a compact shape lacks beta structure entirely fully functional myoglobin molecule has a polypeptide chain plu...

Biochemistry
BIOCHEM 3G03
Daniel Yang
BIOCHEM 3G03 Lecture Notes - Lecture 4: Imidazole, Surface Charge, Amine
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Protein Structure Amino Acids, the Building Blocks of Proteins each protein consists of one or more polypeptides an amino acid has an amino group (-NH3+) and a carboxylate group (-COO-) at physiological pH the carboxyl gro...

Biochemistry
BIOCHEM 3G03
Daniel Yang
BIOCHEM 3G03 Lecture Notes - Lecture 7: Turnover Number, Enzyme Kinetics, Reaction Rate Constant
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Introduction to Enzyme Kinetics the progress of any reaction can be expressed as velocity (v), either the rate of disappearance of the substrate (S) or the rate of appearance of the product (P) [S] and [P] represent the mo...

Biochemistry
BIOCHEM 3G03
Daniel Yang
BIOCHEM 2EE3 Lecture Notes - Lecture 6: Riboflavin, Thiamine, Niacin

DietPlanning Guides: Based on nutrient profile, common agricultural origin, dietary use of foods, and traditional classification. 4 Major Food Groups: Vegetables Fruit contribute carbohydrate, fibre, folate, vitamin ACK...

Biochemistry
BIOCHEM 2EE3
Steven McDonald
BIOCHEM 2EE3 Lecture Notes - Lecture 3: Dietary Reference Intake

Analyzing ResearchFindings: Correlations and causes. Largescale epidemiological observations used by media; all you get back is a correlation. Correlation is not causation. Positive Correlation = same direction; Negati...

Biochemistry
BIOCHEM 2EE3
Steven McDonald
BIOCHEM 2EE3 Lecture Notes - Lecture 3: Molybdenum, Manganese, Fluoride

Energy in the Body: Uses energyyielding nutrients as: o Fuel supports all body activities (carbs); storage for later use (proteins, fats). o Raw materials for building the bodys tissues and regulating activities (particul...

Biochemistry
BIOCHEM 2EE3
Steven McDonald
BIOCHEM 2EE3 Lecture Notes - Lecture 4: Ferritin, Transferrin, Hemoglobin

Requirement for Iron Determined by: Hemoglobin (functional unit). o Contains iron; too little iron results in anemia. o Younger children iron deficiency = slower brain development. Consume iron to prevent hemoglobin decl...

Biochemistry
BIOCHEM 2EE3
Steven McDonald
BIOCHEM 2EE3 Lecture Notes - Lecture 6: Nutrient Density, Cardiovascular Disease, Saturated Fat

Further Guidance: Vegetables Fruit: Eat at least one dark green and one orange vegetable each day (for folate and vitamin A intake). Have vegetables and fruit more often than juice (for fibre intake and lack of added su...

Biochemistry
BIOCHEM 2EE3
Steven McDonald
BIOCHEM 2EE3 Lecture Notes - Lecture 1: Energy Density, Food Energy, Carbohydrate

CHAPTER 1 General Nutrition: Nutrition: The science of foods, and the nutrients they contain and their actions within the body. Includes social, economic, cultural, and psychological implications of food and eating. Food...

Biochemistry
BIOCHEM 2EE3
Steven McDonald
BIOCHEM 2EE3 Lecture Notes - Lecture 2: Dietary Fiber, Food Energy, Starch

CHAPTER 2: Food Labels: 3 main sections of nutrition information on a food label: o Nutrition Facts table, ingredients list, claims. Serving Size: Serving sizes may differ due to different measures used. Serving sizes d...

Biochemistry
BIOCHEM 2EE3
Steven McDonald
BIOCHEM 3H03 Lecture Notes - Lecture 14: Antigen, Endocrinology, Cortisol
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BIOCHEM 3H03 LECTURE 14 Generalized competitive immunoassay o Antigen excesso Pick a hormone and the corresponding antibody for it (black things) o Addspecimen(withtheanalyteinit,blueballs)andalsoaddthe label...

Biochemistry
BIOCHEM 3H03
Stephen Hill

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