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BIOLOGY 1M03 (677)
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1MO3_Chapter 14.docx

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Department
Biology
Course
BIOLOGY 1M03
Professor
Jon Stone
Semester
Winter

Description
Human Genetic Variation Human VariationHumans vary in many different waysPhysical appearance skin color heightSkills preferencesVariation in human disease Humans Variation vs Plant VariationIt is very helpful to control parent mating and to separate groups of offspring and grow them in known conditions In shortlived model organisms we can start with lines that are homozygous also called purebreeding or truebreeding With peas Mendel could self them for generations to ensure they were true breeding Cant do this with humans Variation in Traits Influenced by Single GenesGenetic variation o Ex Sicklecell anemiaSpecific Language Impairment SLI o Runs in families o Pattern of inheritance consistent with dominant allele at single locusFOXP2 gene Causes of Genetic Variation within GroupsSelectionmutation balance o If gene freq of PKU allele is 0001 freq of babies with PKU is 0000001Balanced polymorphism o Heterozygous individuals have highest fitness Variation in Complex Phenotypic TraitsMany traits influenced by many different genes o Ex Bellcurve distribution o Heritability o Environment affect covariation Variation in Complex Phenotypic TraitsTwin studies o Monozygotic o D
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