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McMaster University
Douglas Davidson

Ch 11: Schizophrenia  Schizophrenia is a psychotic disorder characterized by major disturbances in thought, emotion, and behaviour: disordered thinking in which ideas are not logically related, faulty perception and attention, flat or inappropriate affect, and bizarre disturbances in motor activity  Patients with schizophrenia withdraw from ppl and reality often into a fantasy life of delusions and hallucinations  Schizophrenia is one of the most severe psychopathologies; however its life time prevalence is generally accepted to be about 1%  Concluded that there may be real variation in schitzo across geographical regions around the world with Asian populations having the lowest prevalence rates  Higher in males than in females (male- female = 1:4)  Although schitzo sometimes begins in childhood it usually appears in late adolescence or early adulthood or early adulthood somewhat earlier for men than for women  Ppl with schitzo typically have a # of acute episodes of their symptoms.  Between episodes they often have less severe but still very deliberating symptoms.  Most ppl with schiotzo are treated in the community however hospitalization is sometimes necessary  Concluded that almost one half (46%) do not require inpatient services. However ppl who were 1 diagnosed while inpatients and those residing in rural areas were most likely to require additional st inpatient services in the 1 year of treatment  In Canada hospitalization rates are typically much higher among young men relative to young women accounting for 19.9% of separations from general hospitals. Scitzo accounts for 30.9% of separations from psyiatric hospitals  About 10% of ppl with scitzo commit suicide  Many ppl with scitzo remain chronically disabled. The disability can be attributed to symptoms inherent to schitzo as well as the comorbid disorders from which approx 50% of those with shcitzo suffer  In 2004 there were an estimated 234,305 ppl in Canada with schozto. Overall 374 deaths that year were attributed to schizto. The illness total costs were $6.85 billon 70% of which was the cost of lost productivity Schizophrenia and comorbidity  Comorid conditions appear to play a role in the development, severity and course of schito. Comorbid substance abuse is a major problem for patients with schizto occurring in as many as 70% of them  37% of the sample of ppl with schizto showed current evidence of substance us disorders. The relationship was especially common among men and analyses suggested that childhood conduct disorder problems are potent risk factors for substance use disorders in shcizto  about 40% of the participants were depressed at the outset. Over the next three years those diagnosed with shcizto who were also depressed relative to the non depressed group were more likely to use relapse related mental health services to be a safety concern, to have substance related problems and report poorer life satisfaction, quality of life, mental functioning, family relationships and medication adherence.  Comorbid anxiety disorders are also common and can impose an additional burden on ppl with schizo and results in further decline in their perceived quality of life.  Comobidity with obsessive compulsive disorder is also related to a previous history of suicidal ideation and suicide attempts  Post traumatic stress disorder is highly prevalent and under diagnosed among military veterans with shizto  Developing( prodromal) phase of schito. Found that prodomol patients experience a wide variety of comorbid psychiatric syndrome especially major depressive disorder and cannabis dependence CLINICAL SYMPTOMS OF SCHIZOPHRENIA  The symptoms of patients with shcizto involve disturbances in several major areas: thought, perception, and attenti
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