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Lecture 1

BIOLOGY 2A03 Lecture 1: 1) Intro to Physiology
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Department
Biology
Course
BIOLOGY 2A03
Professor
Graham R.Scott
Semester
Winter

Description
1) Intro to Physiology Wednesday, January 4, 2017 11:29 AM Office hours - Mondays 2-3:30 LSB 227 Office hours: LSB 227 MONDAYS 2-3:30 TEST FEBRUARY 3RD MARCH 10th Sinah lee - intructional assistan-t [email protected] Labs worth 30% Lectures 1-4 : Chapters 1 -5 in text. - Physiology tries to understand how organisms function, and the underlying mechanism. - Integrative - Function of the proteins that interact to dictate how cells operate. - Mechanisms are fundamental. Integrative - Environmental physiology - How our bodies and other organisms bodies work - Understanding challenging environments and how physiology supports living in them Comparative physiology - Diversity in how the systems work - Aligned to evolutionary biology - differences between organisms and how they work. Medical physiology and pathophysiology - How physiology can go wrong - pathogens. 3 they work. Medical physiology and pathophysiology - How physiology can go wrong - pathogens. 3 Compare and contrast states to understand how our bodies operate. Pathophysiology-contrast a normal individual to someone where something has gone wrong. Ie heart failure = reduction in oxygen supply to body tissues. - Understand principles (oxygen delivery) Comparative physiology - Understand how oxygen is supplied to mitochondria by looking at animals that live with little oxygen in the air. - Normal organisms to one that can hold their breath for over an hour. 4 Hierarchical organization of the body. - Need to define the levels - Cells to organisms 1) Cells-differentiated into categories - A)Muscle b)Nerve c)Epithelial d)Connective A) Muscle - Responsible for movement. - Skeletal-voluntary, conscious control over. - Cardiac - movement of heart. - Smooth- dilation of blood vessels, peristalsis in gastro system. B) Nerve Cells - Thinking and electrical systems. - Important for underlying thought, memory, and our movements. C) Connective Tissue Cells - Most diverse (many types) - Supportive role - bone and collagen, - Non supportive - blood cells. - All develop from the same primordial cell in development. D) Epithelial Cells - Supportive role - bone and collagen, - Non supportive - blood cells. - All develop from the same primordial cell in development. D) Epithelial Cells - Barrier and separating parts of the body. - Secretion and absorption of substances. 2) Tissues- collection of myocytes or muscle cells together 3) Functional Units - collections of cells,s ubunits of an organ. - Ie nephrons in the kidney - Multiple types of cells together. 4) Organs - Many different types of cells to make it up, two or more tissues. - Differentiated from a single functional unit bc its an INTACT structure like a heart or kidney. 5) Organ systems - Coordinated function for a common goal. - Circulatory system -heart, blood vessels and blood to move things around the body. TABLES - NOT REQUIRED TO LEARN EVERYTHING IN THEM. Unless he explicitly says we have to know it all - don’t memorize and read tables. 9 Simplified view of the body of an organism - External environment is barrier to internal We interact with our environment - - Gas exchange structures, acquiring nutrients from our environment, water or inorganic ions. - Circulatory systems move things around ie gasses and nutrients. - Takes them to various cells (circulatory convective systems) - Take things away from cells as well. - Other end - getting rid of stuff we don’t want. - Waste products and toxins that are removed and excreted. Key aspect*** - things in our internal environment are VERY constant, the internal environment is stable in our body, even when the EXTERNAL - Other end - getting rid of stuff we don’t want. - Waste products and toxins that are removed and excreted. Key aspect*** - things in our internal environment are VERY constant, the internal environment is stable in our body, even when the EXTERNAL environment changes. …….. THIS IS HOMEOSTASIS. 10 Internal environment = water (60%) Terms: Intracellular fluid- in cells, part of the water in our body, or in red blood cells Extracellular fluid- outside of cells - - of this, some is in our circulatory system ( plasma) - Of this, some is interstitial fluid (not in circulatory system). Intracellular fluid = inside cells, part of water, red blood cells. Extracellular- plasma + interstitial fluid. 11 Total body water is broken down… most iI sNSIDE our cells (2/3) 1/3 outside our cells -much is not
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