BIOLOGY 2B03 Lecture Notes - Lecture 5: Unfolded Protein Response, Golgi Apparatus, Glycosyl

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Describe protein modifications that occur in the rer. Describe the process of the unfolded protein response. Can highlight the er specifically using antibodies. All the membranes of the cell are visible. Membranes are very dynamic and undergo constant change in structure. 2 components of the endoplasmic reticulum: rough endoplasmic reticulum (rer) Studded by ribosomes attached to the membrane of the er. Transport occurs between the rer and the golgi apparatus: proteins synthesized in the rer are moved via vesicles to the golgi apparatus. Synthesis of fatty acids and phospholipids occurs. Addition of carbohydrate moieties to a protein. Primarily found on proteins that are secreted or plasma membrane proteins that have exoplasmic domain proteins. There are 2 types of glycosylation events: n-linked. Addition of oligosaccharide block" to nh2 group of asn: o-linked. Addition of 1-4 sugar residues to oh group of ser, thr.

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