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BIOLOGY 2B03 (285)
Kim Dej (39)
Lecture 8

Lecture 8 Summary

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Kim Dej

Lecture 8Cell Adhesion Summary Tight Junctionsfluidsmolecules nothing can escape Added Lanthanum hydroxidebetween cells Wouldnt show up in TEM passed the tight junction Gap junctions can cross through neighboring cells Donut shaped pores connect neighboring cellsProteins make up the wall of the channel Each channel made up of proteins that reside in each of the neighboring membranes Channels connect cytoplasms of both cells Only molecules smaller than the pore size of 2nm can flow through certain ions proteins fluoresceins and campIe fluorescein not common in the human body but it is small enough and secondary messengers like cAMP Muscle movements controlled by movement of 2ndary messengers through the channel Gap Junction many channels comprise a junction Intercellular space between 25nm to 3nm Junctions allow cells to have stable associations between cells and also communicate between cells Interactions can be broken endothelial cells specialized epithelial cells form inner lining of the blood vessels Leukocytes respond to infections Leukocytes must move out of the blood vessel into damaged or infected tissue extravastion Movement of leukocytes depends on precise sequence of adhesive interactions Inflammatory response Local infections bacterial viral or injury rapidly attract white blood cells to the affected regionsLeukocytes1 Granulocytestoxins for killing path
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