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BIOLOGY 2C03 (138)
Kim Dej (45)
Lecture

Myelination

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Department
Biology
Course
BIOLOGY 2C03
Professor
Kim Dej
Semester
Fall

Description
Outline of Lecture 15 (02-21 B; Griffin) Myelination I. Schwann cells and oligodendrocytes: the myelin forming cells of the PNS and CNS - Myelin sheaths speed conduction and cause saltatory conduction - Spaces between sheaths, the nodes of Ranvier, are sites of dense Na channels, where action potential is regenerated A) Schwann cells (3 types) - Satellite cells: found in enteric system, isolate neurons from surrounding environment - Ensheathing Schwann cells: surround nonmyelinated PNS axons, multiple axons per SC - Myelinating Schwann cell - One axon per Schwann cell; the axon induces myelin formation - Unrolled forms trapezoid shape, explains distinctive edge morphology - Major dense line is the cytoplasmic face of membrane; intraperiod line is extracellular face - Does no
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