BIOLOGY 3UU3 Lecture Notes - Lecture 4: Corticosterone, Homeostasis, Allometry

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Wakefulness: hypothalamus is the center all the information is being referenced to each other then sent out to various regions of the brain. All these phases are associated with various functions hormone upregulation, activity in different parts of the brain: spatial and temporal specification of these processes. Clock providing an input to the sleep cycle: upregulation of stress hormone axis, orexins hormonal group that increases arousal during the day time and is involved in waking you up in the morning. Sleep has a hallmark of physiological functions for homeostasis: ex. If you stay up for 3 days you"ll sleep more afterwards catch up aspect: incurs costs that have to be made up doing something critical/fundamental to the organism which is why all animals sleep. Clock scn and sleep homeostat (outside scn) are two major determinants of the timing of the human sleep-wake cycle and sleep structure: oscillation of sleep homeostat is strongly, and exclusively, determined by the sleep wake cycle.

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