BIOLOGY 1A03 Lecture Notes - Lecture 3: Peptide, Escherichia Coli, Gene Expression

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BIOLOGY 1A03 Full Course Notes
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BIOLOGY 1A03 Full Course Notes
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Why is it important to regulate the expression of enzymes: enzymes are required to metabolize nutrients, cells must be able to metabolize macromolecules like carbohydrates into sources of atp. However, they start growing again quickly when they start metabolizing lactose. General properties of glucose metabolism: glucose is a monosaccharide, lactose is made of one molecule glucose and galactose, so when direct glucose is not available, the cell metabolises the disaccharide lactose. B-galactosidase: the enzyme that metabolizes lactose to produce glucose and galactose; produced by turning on transcription of the b-galactosidase gene. Transcriptional control to allow for the transcription of dna to mrna. Translational control to allow for the translation of mrna to proteins. Post-translational control to allow for modifications and activation of produced proteins. When glucose is depleted from environment where e. coli cells are growing, the cells transcriptionally regulate and increase levels of b-galactosidase to allow for lactose metabolism.

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