BIOLOGY 1A03 Lecture Notes - Lecture 2: Cystic Fibrosis, Human Genome Project, Francis Collins

• School: McMaster University
• Department: Biology
• Course: BIOLOGY 1A03
• Professor: Nathan Upham

Document Summary

Because something went wrong at the nucleic level and at the protein level. The airway of the trachea is enveloped by mass of mucus. Can lead to bacterial infections influenced by inflammation. Many effects on the body, but mostly affects digestion and lungs. With chronic persistence and bacterial infections, destruction of lung leads to most prevalent cause of death. They don"t present symptoms of cystic fibrosis because they only each have 1 copy of the gene. Can affect respiratory tract and even reproductive organs. Everyone has a thin film of mucus in our body but cystic fibrosis people have thick layer which is hard to clear from the lung which leads to a persistent cough trying to clear the airways. Overtime there is more wheezing due to narrowing of airways. Bowel disturbances very common, they don"t have a thin mucus that would help bowel material pass by.