Theme 2, module 1-transcription the central dogma: the process of copying and interpreting genes into proteins (dna mrna protein) All prokaryotes utilize a single type of rna polymerase: initiation of transcription is dependent on the association of rna polymerase with sigma factor proteins that facilitate the binding to the promoter region. Consensus sequence: the most common nucleotides found at a specific dna/rna location (ex. Transcription/translation is coupled in prokaryotes because they lack compartmentalization. Prokaryotes have 2 types of terminator sequences: row independent terminator sequences: inverted nucleotide repeat sequences. When transcribed the rits fold back onto themselves forming a gc rich hairpin loop along the rna strand. Pauses rna polymerase and releases mrna transcript: row dependent terminator sequences: uses a protein/row factor. Binds to rna transcript and uses atp to move along it. Unwinds the rna transcript from the dna template.