BIOLOGY 1M03 Lecture Notes - Lecture 7: Allele Frequency, Gene Flow, Heterozygote Advantage

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9 Aug 2019
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Founder effects in human evolution: when you have a source population and a subset of that population moves to another location (disperses, human diaspora from africa was associated with multiple founder effects. What is a population: a population is a group of individuals (usually from the same region) that has different allele frequencies from another group of individuals (usually from a different region, gene flow homogenizes allele frequencies across populations. Nature of gene flow in humans: ex. Gene flow between people of african and european ancestry in america. Expectation- with no bias in mate pairing (no difference in pairing between black males and white females vs. white males and black females) suggest bias in mate pairing- in contemporary african. American people, different portions of the genome have different proportions of european ancestry. Nonrandom mating: in nature, mating may not be random with respect to any particular gene, examples of biased mating- inbreeding and sexual selection (violate hwe)

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