BIOLOGY 1M03 Lecture Notes - Lecture 4: Genotype Frequency, Allele Frequency, Melanism

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The hardy-weinberg principle a null hypothesis that predicts what genotype frequencies should be given known allele frequencies. Allele frequency frequency of each variant (e. g. a1 allele) Genotype frequency frequency of each genotype (e. g. a1a2 genotype) Phenotype frequency frequency of each phenotype (e. g. dark colour in a moth) Two populations with the same allele frequencies can have di erent genotype frequencies. Frequency of two alleles can be equal, but one can be dominant over another. Hardy-weinberg principle examines probability of each genotype frequency. Establishes expectation for di erent phenotypes based on allele frequencies. Modi es allele frequencies by continually introducing new alleles, even deleterious ones. Posited idea of a gene pool of parental genes. Imagines all gametes produced go into this group. H-w principle holds when following 5 assumptions/conditions are met with respect to the gene in question: no natural selection, no genetic drift (stochastic allele frequency changes, no gene ow (migration, no mutation, no biased mating.

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