BIOLOGY 1M03 Lecture Notes - Lecture 1: Assortative Mating, Stabilizing Selection, Autosome
16 Feb 2016
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Document Summary
Different markers tell different stories; need markers with appropriate resolution. Y chromosome tells you where the men ancestry comes from. Mitochondrial- tells you where you female ancestry comes from. Markers types: single nucleotide polymorphisms (snp), microsatellite markers (repetitive, rapidly evolving, haplotypes non-recombing, inherited as a unit. Low variation among human populations relative to among species variation in chimps. Much more divergence both within and between chimp species than within. I-clicker which of the following is the least: stronger stabilizing selection, weaker diversifying selection, smaller population sizes, lower mutation rates, stronger assortative mating. Times with small population size have more branching. We can reconstruct tress from genetic data to create size history. Find most common ancestor (mrca) of current day haplotypes. Africa australia then africa europe. Climate more suitable for moving to australia 72- 60 kya. Certain populations goes through intense bottle necks ie. the french goes through a larger bottleneck than san.
