BIOLOGY 2B03 Lecture Notes - Lecture 4: Peroxisome, Cytosol, Actin

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Nerve cells: plasmalogen synthesis for cellular membranes to increase insulation. Plant cells; convert fatty acids carbohydrates, especially in seeds for their germination. Peroxisomal proteins produced in cytosol and transported to peroxisome. Membrane protein pmp70 used to create peroxisomal ghost to transport peroxisomal matrix proteins into interior of cell. As more proteins are synthesized, peroxisomes grow and undergo fission to make more peroxisomes o o o. Import receptor recognizes the motif by entering a hydrophobic binding pocket, interacting with hydrophobic. If entering the matrix, it will also interact with tim44, Tim23 and tim17 complex in the inner membrane at. Contact sites": two translocons aligned to allow direct movement through openings in inner ad outer membranes. The inner membrane opens laterally and the hydrophobix helix interacts and travels through membrane and then embeds itself; translocon closes once complete. Stop transfer sequence is necessary, otherwise protein would just go to the matrix. Hyrodphobic peak for the sa sequence.

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