BIOLOGY 2EE3 Lecture Notes - Lecture 1: Eukaryote, Phosphorylation, Recbcd
12 Aug 2016
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A + oric b (helicase) and c (loader) recruited. Dna pol 1 releases primers & fills gas. Rna pol separates dna & creates comp strands. Sigma factors bond to rna pol core enzyme. Diff sigma factors may direct core to different genes. Rho dependent rho prot pops out pol at term site. Rho indie dna sequence makes hairpin loop. Individuals trans fact prot ass with promoter regions. Rna pol (possible 3) recruited to trans fact dna complex. Binding initiates unwinding of dna and start of trans. Term complex depends on rna pol 1 2 or 3. Dna is mod"d with cap or tail, introns out exons in. Ribosome + mrna trna with aa delivered. Codon & anticodon don"t need to match wobble (20aa) Small rib and shin dal seq align machinery to start loc. Virus can make vif to stop apobec36 (hiv) Host rec are critical for fxn so hard to eliminate.
