BIOLOGY 3UU3 Lecture Notes - Lecture 23: Lipofuscin, Autophagy, Life Extension
4 Apr 2016
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Document Summary
Stress hormone axis involved in late sleep to help you wake up. First thing when you wake up is go for food. As you age, there is a dramaic decline in growth hormone secreion elevaion in stress axis in response to senescence. Increasing oxidaive stress as it ages could contribute, dna damage, telomeres (not a universal theory of aging mice don"t have shortening of telomeres) Waking, slow wave and rem sleep are the three stages all phases decline with age. To return to youthful state get them all back up (not shut down tor to raise stress axis sill want a balance) In old people lower everything (hormones, aciviies reduced, etc. ) Geriatric people are largely associated with fragmented sleep (more like a shrew), don"t go into deep, slow wave sleep, more rem which is associated with sa. Longevity and aging rates may relect extrinsic mortality pressures. Some systems can be manipulated when species live longer.
