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Class Notes for Biotechnology at McMaster University

BIOTECH 4BM3 Lecture Notes - Lecture 7: Biopharmaceutical, Post-Translational Modification, Periplasm
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Pharmacology Notes The Drug Manufacturing Process Part III Sources of Biopharmaceuticals -Vast majority of biopharms on the marker are produced by genetic engineering (proteins) -Most of these products so far are mad...

Biotechnology
BIOTECH 4BM3
Dr.R
BIOTECH 4BM3 Lecture Notes - Lecture 4: Lead Compound, Drug Design, Paroxetine
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BIOTECH 4BPM3 Biopharmaceuticals - Lecture 4 NMR vs X-ray Crystallography (advantages/disadvantage) NMR A-in solution (37 degree Celsius) can se the dynamic structure D-need a huge amount of proteins (could assume di...

Biotechnology
BIOTECH 4BM3
Dr.R
BIOTECH 4BM3 Lecture Notes - Lecture 3: Peptide, Edman Degradation, High-Performance Liquid Chromatography
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BIOTECH 4BPM3 Biopharmaceuticals - Lecture 3 Gene Neighbour Method -Computation-based -If two genes are consistently found side by side in the genome of several different organisms, they are likely to be functionally...

Biotechnology
BIOTECH 4BM3
Dr.R
BIOTECH 4BM3 Lecture Notes - Lecture 2: Bioinformatics, Gene Knockout, Biopharmaceutical
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BIOTECH 4BPM3 Biopharmaceuticals - Lecture 2 Life History of a Successful Drug -Drug Discovery -Initial characterization -Pre-clinical trials -Regulatory approval for human trials -Clinical trials -Phases I,...

Biotechnology
BIOTECH 4BM3
Dr.R
BIOTECH 4BL3 Lecture Notes - Lecture 1: Materials Science, Hydrogen Bond, Biocompatibility
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BIOTECH 4BL3 Biomaterials and Biocompatibility Lecture 1 Material Science investigates relationship between materials structure and properties Material Engineering based on materials science, designing and engineeri...

Biotechnology
BIOTECH 4BL3
Amin
BIOTECH 4BM3 Lecture Notes - Lecture 1: Cardiac Glycoside, Biopharmaceutical, Corticosteroid
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BIOTECHNOLOGY 4BM3 Biopharmaceuticals Lecture 1 Pharmaceuticals -very broad term -central to modern medicine -most are low molecular mass organic chemicals (0.5-1 kDa) -to pass through biological membrane ...

Biotechnology
BIOTECH 4BM3
Dr.R
BIOTECH 3PM3 Lecture Notes - Lecture 13: Isosorbide Mononitrate, Isosorbide Dinitrate, Coronary Artery Disease

McMaster University BIOTECH 3PM3 Pharmacology Week 13 Antianginal Drugs Angina pain that arises in the chest from lack of oxygen in the blood Coronary Arteries -supply essential nutrients and oxygen to the heart ...

Biotechnology
BIOTECH 3PM3
Dr.R
BIOTECH 3PM3 Lecture Notes - Lecture 5: Cholinergic, Adrenergic, Postganglionic Nerve Fibers

McMaster University BIOTECH 3PM3 Pharmacology Week 05 Activation of Parasympathetic and Sympathetic Pathways -when the sympathetic division is stimulated, all sympathetic nerves are activated at the same time ...

Biotechnology
BIOTECH 3PM3
Dr.R
BIOTECH 3PM3 Lecture Notes - Lecture 4: Central Nervous System, Peripheral Nervous System, Sympathetic Nervous System

McMaster University BIOTECH 3PM3 Pharmacology Week 04 Introduction of the Autonomic Nervous System Nervous System Organization Central Nervous System (CNS) -Compromised of the brain and spinal cord -Integrates a...

Biotechnology
BIOTECH 3PM3
Dr.R
BIOTECH 3PM3 Lecture Notes - Lecture 3: Bioavailability

McMaster University BIOTECH 3PM3 Pharmacology Week 3 Drug Distribution The manner in which a drug is transported from the site of absorption to the site of action Blood flow -muscle, brain, fat Binding to protei...

Biotechnology
BIOTECH 3PM3
Dr.R
BIOTECH 3PM3 Lecture Notes - Lecture 2: Dosage Form, Subcutaneous Tissue, Starch

McMaster University BITOECH 3PM3 Pharmacology Week 02 Drug Dosage Form -Comes in various dosage forms -the physical and chemical properties of a drug will determine how affective it is Tablets vs Capsules Table...

Biotechnology
BIOTECH 3PM3
Dr.R
BIOTECH 3PM3 Lecture Notes - Lecture 1: Inverse Agonist, Pharmacodynamics, Antihistamine

McMaster University BIOTECH 3PM3 Pharmacology Week 01 Pharmacodynamics Site of Action Location where drug exerts Receptors are mostly proteins (95) Ligand (aka interaction of drugs) Mechanism of Action How does drug produc...

Biotechnology
BIOTECH 3PM3
Dr.R

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