HTHSCI 1H06 Lecture Notes - Lecture 2: Ductus Venosus, Ductus Arteriosus, Ligamentum Arteriosum

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Cardiovascular develop(cid:373)e(cid:374)t: postnatal (adult) vs fetal circulation (where does vascular resistance differ and why?, changes in vascular resistance at birth (pulmonary vs systemic circuits) In a fetus, the two systems mix oxygenated and deoxygenated blood together. In postnatal, the interventricular septum has formed, and the right side holds deoxygenated blood whereas the left side holds oxygenated blood: adult vs fetal. In an adult circulatory system, pressure is higher in the left side of the heart. In a fetus, the pressure is higher in the right side of the heart: specializations: placenta, umbilical veins, ductus venosus, foramen ovale, ductus. Sinus venosus: turns into right atrium, sa node and coronary sinus: division of truncus arteriosus, aorticopumonary (spiral) septum. Formation of interatrial septum (steps from septum primum -> foramen ovale: endocardial cushion is the landmark for the formation of the septum in the heart, septum primum comes down towards the endocardial cushion, but doesn"t quite reach the.

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