HTHSCI 3I03 Lecture Notes - Lecture 10: Memory T Cell, Memory B Cell, Adaptive Immune System
Document Summary
Measles was introduced to the faroe islands in 1781, and caused a severe epidemic affecting the entire population. More than 60 years later, in 1846, measles was again introduced. Almost all of the 5000 inhabitants who had been born since the first epidemic developed the disease. But all 98 survivors of the 1781 epidemic proved resistant; they had retained sufficient immunological memory to prevent their 2nd exposure from causing disease. During successful primary infection 2 goals are achieved: developed effector cells and molecules that end infection as soon as possible, building up immune memory, a reserve of long lived b and t cells called memory cells. After a period of time you see antibodies being made against infectious agents as well as effector t-cells. The effector t-cells ramp up faster than antibodies. Generally only last a few weeks then will go down (effector t-cells)