HTHSCI 3I03 Lecture Notes - Lecture 8: High Endothelial Venules, Lymph Node, Viral Disease

• School: McMaster University
• Department: Health Sciences
• Course: HTHSCI 3I03
• Professor: Martin Stampfli

Document Summary

Cd8 and cd4 are co-receptors that are required for optimal interaction of tcr with. Cd8 binds alpha3 domain of mhc class 1: target cell. Cd4 binds the beta-2 domain of mhc class 2: antigen-presenting cell. Endogenous pathway made through the process of infection around, the things that t-cells can be interested in: those proteins are transcribed in the nucleus and translated. Antigen presenting cell= shop window to immune system, displays what"s: proteins generated within the cell self proteins, or viral proteins. Predominantly a cd4 mhc class 2 route bacterium, bits of virus. Na ve t cells monitor antigens presented by dendritic cells. Na ve t cells can only be activated in lymphoid tissues: typically lymph nodes. Activation of na ve t cells can only occur with professional apc (like dc: dendritic cells, b-cells, macrophages, dendritic the best apc. The process of activating the effector function in na ve t cells is known as.