HTHSCI 3I03 Lecture Notes - Adaptive Immune System, Innate Immune System, Gnathostomata

164 views20 pages

Document Summary

The first lines of defense (barriers to infection) Pathogen recognized by receptors (prrs) encoded in the germ line. Receptors are b-cell (bcr) and t-cell (tcr) receptors, huge repertoire. To prevent attachment and/or entry of pathogenic microbes into the host epithelial cells, while allowing growth of beneficial microbes. To recognize, control and eliminate pathogenic microbes at the site of entry. To induce inflammation and bring extra help to the site of infection. To orchestrate an appropriate and measured adaptive immune response. Epithelial surfaces provide the first line of defense urogenital. Skin: the largest organ (12-15% of body weight) Healthy skin is very resistant to viral and bacterial infections. Epithelial cells of the mucosa and mucus layer renew very frequently (every 24-48 hrs) Important payer of innate immunity and much more! About 2. 8 kg bacteria in the gut mucosa alone! Normal flora (microbiota) prevent infections, in part, by: 1- filling almost all of the available surfaces; keeping the bad bugs out.

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents