HTHSCI 1H06 B Lecture Notes - Lecture 15: Pepsin, Enteroendocrine Cell, Carbonic Anhydrase

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Gastrointestinal System
1
-3 phases
-voluntary, pharyngeal, and esophageal (listen)
-food through thoracic cage, to diaphragm to lower esophageal sphincter
Basic Plan
- Mucosa
-Submucosa has blood vessels, nerves, and submucosal glands
-Muscularis with outer longitudinal and inner circular layer
-Serosa has mesothelium and thin CT (glue)
enteric
-in wall of elementary canal
-can function independently without need of SC to add input
-coordinates contractions to move from gut to bum
-2 components
-myenteric plexus
-submucosal plexus (controls epithelium of submucosal glands and epithelium)
-Has interstitial cells of Cajal which are the pacemakers
-parasympathetic can control rate, sympathetic can slow it down
ANS
-food causes stretch, change in ph, which are sensed and info is shared with myenteric then
submucosal
-info is also shared with CNS (too much distention = pain)
Sympathetic innervation
Folds
-greater momentum is a source of excess energy (fats)
-fat, good blood supply, macrophages
-lesser momentum is the peritoneum that extends ….
-mesentery suspends lower intestines from __ wall
5 folds
-peritoneum goes over stomach and forms flap = greater
-transverse portion of large intestine
-mesentery suspends small intestine from posterior abdominal wall
-suspends liver and attaches to interior abdominal wall = falciform ligament
Stomach
-rugaE - INTENSE FOLDS OF MUCOSA to allow stomach expansion
-oblique layer- churns at food helping to mix gastric secretion with food to break them down
-serosa = visceral peritoneum
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Document Summary

Food through thoracic cage, to diaphragm to lower esophageal sphincter. Submucosa has blood vessels, nerves, and submucosal glands. Muscularis with outer longitudinal and inner circular layer. Serosa has mesothelium and thin ct (glue) enteric. Can function independently without need of sc to add input. Coordinates contractions to move from gut to bum. Submucosal plexus (controls epithelium of submucosal glands and epithelium) Has interstitial cells of cajal which are the pacemakers. Parasympathetic can control rate, sympathetic can slow it down. Food causes stretch, change in ph, which are sensed and info is shared with myenteric then submucosal. Info is also shared with cns (too much distention = pain) Greater momentum is a source of excess energy (fats) Lesser momentum is the peritoneum that extends . Mesentery suspends lower intestines from __ wall. Peritoneum goes over stomach and forms ap = greater. Mesentery suspends small intestine from posterior abdominal wall. Suspends liver and attaches to interior abdominal wall = falciform ligament.

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