HTHSCI 1LL3 Lecture Notes - Lecture 5: Globular Protein, Alpha Helix, Beta Sheet
24 Feb 2016
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Document Summary
The conformation (or shape) of a protein predicts its function- proteins held in their shape mostly by non-covalent bonds. There are several different general types of structure for proteins. Globular proteins (big and round), fibrous proteins, transmembrane proteins (receptor on outside and part of the protein inside the cell), and dna binding proteins (positively charged as. Dna is a very negatively charged molecule) are major classifications for the different types. Collagen is a structural and a fibrous protein. Hemoglobin is a globular protein, and also polar. The amino acids will be in places where they are compatible with their environment. Primary structure- list of amino acids in the correct order, the list comes from dna. Secondary structure- has different folding elements: alpha helices and beta sheets. Tertiary structure- how the molecule folds into its three dimensional shape. Quaternary structure- when there are multiple subunits/chains (in the above picture it is a tetramer as it has 4 subunits).
