HTHSCI 2C06 Lecture Notes - Lecture 9: Subtypes Of Hiv, Night Sweats, Reverse Transcriptase
2 May 2016
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Document Summary
Contains 3 lines of defence: first line- intrinsic barriers (skin and mucus membranes) Mechanical (coughing, sneezing, defication and urination means of ridding infection before they can breach mucus membranes) Chemical low ph barriers prevent pathogenic colonization, and enzymes in gut breakdown bacteria. Microbiological flora competes with pathogens for resources: second line- innate immunity (contains various wbc [phagocytes, nk cells etc. ], the inflammatory response, protein complement systems and fever: third line- adaptive immunity. Goal: to eliminate pathogens that may have circumvented the first two lines of defence and to confer protection from new, emerging strains of pathogens . This line of defence involves the cellular and humoral response. The cellular response focuses on killing of abnormal cells. The humoral response focuses on production of antibodies that provide body protection. Malt (mucosal associated lymphoid tissue)- includes adenoids, tonsils, and peyers patches. The location of malt is key to its function.
