HTHSCI 2S03 Lecture Notes - Lecture 1: Statistical Inference, Hand Washing, Nonprobability Sampling

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Use of rigorous methods to develop, refine, and expand knowledge to answer questions or solve problems . Knowledge generation process is very much quantitative. First step is identifying the question or problem. States the problem the researchers want to solve or contribute to its solution: research question. States the actual question that the researchers want to. Research question: (p) in patients receiving chemotherapy, (i) what is the effectiveness of patient-controlled antiemetic therapy, (c) versus nurse-controlled antiemetic therapy, (o) on medication consumption and control of nausea and vomiting. Two types of questions/problems: quantitative, qualitative. The course will focus on quantitative questions/problems. The research design depends on the question/problem. Non-experimental: case-control study, cohort study, cross-sectional study. Randomization to groups: treatment or control. Measure outcome forward in time (recurring atherosclerosis: before and after intervention, after intervention only. Each participant has an equal chance of being assigned to any of the study groups.

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