HTHSCI 3I03 Lecture 1: Intro to Immunology
4 Feb 2018
School
Department
Course
Professor
Document Summary
Always an interaction between mankind and infectious disease. A system that maintains homeostasis, protects against outside and inside. If cells are dying, the immune system is left to clean the mess. Physical barriers: epithelial cells, mucus, defensins, tight junctions, keep physical barriers in tact, integrity of barriers is critical. Innate immunity: macrophages, neutrophils, eosinophils, natural killer cells, provide innate protection. They act together, help each other out. In 1979, after 3 years in which no case of smallpox was recoded, the world. Health organization announced that the virus had been eradicated. Vaccination course does not hold off against immune system. Records from 16th century china described the process of inoculation. Pustules from smallpox victims were collected, rendered into powder, and blow up the nose of healthy people: if you survived this you were protected from disease, chinese had a strategy for vaccination. Observed inoculation technique while living in turkey.
