KINESIOL 4B03 Lecture Notes - Lecture 11: Viscosity, Homocysteine, Saturated Fat

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Higher mortality among truck drivers in regards to diseases of the heart. Prevalence of htn highest in: <6 hours (32. 4% prevalence, > 10 hours (32. 5% prevalence) After adjustment for confounders: or 1. 66 (1. 35-2. 04) for <6 hours (66% higher, or 1. 30 (1. 04-1. 62) for > 9 hours (30% higher) Sleep is an independent marker of incident htn. Still see relationship after adjusting for variables. Confounding variables: sleep duration is unrelated for htn in older adults (60-86 years) Increased risk in chd: <6 hours (11% prevalence, >10 hours (14. 8% prevalence) Risk of fatal and non-fatal chd events: less than 7-8 hours (rr 1. 48, 1. 22-1. 80, more than 7-8 hours (rr 1. 38, 1. 15-1. 66) (increased risk by 30-50%) Magnitude of risk decreases when controlling for confounders. Lowest imt in people who sleep for 7-8 hours: each hour of sleep associated with 0. 026 mm decrease in imt. Sns effects the heart (co) and arterioles (peripheral resistance) Heart ateries (bp) aterioles (peripheral resistance)

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