Life Science 3AO3: Health and Disease
Dr. Rosa da Silva LSB540 email: [email protected]
Dr. Luciano Minuzzi
Dr. Angela Scott
Dr. Tim Gilberger
Dr. Ishac Nazi
INSTRUCTIONAL ASSISTANT :
Sunita Nadella BSB 111 email: [email protected]
This course is broken into five modules that look at different topics of human health and disease. Each topic is
examined from several different perspectives, from the molecular biology of the disease, through the physiological
effects, to current and potential treatments. While we focus upon the cell biology, genetics, and biochemistry of each
disease we also consider the social and economic factors that affect disease persistence and treatment. The concep t of
disease eradication will also be considered. This term we will also look at different perspectives on drug
development and design in the context of health and disease.
The topics for this term:
Each module is taught by the instructor indicated in bra ckets:
• Module 1: Depression: Mood disorders (Dr. L. Minuzzi)
• Module 2: Reconstruction of the nervous system following spinal cord injury (Dr. A. Scott)
• Module 3: Cirrhosis of the liver (A. Zimmer)
• Module 4: Malaria: Pathogenesis and Prevention (Dr. T. Gilberger)
• Module 5: Immune-mediated platelet disorders (Dr. I. Nazi)
COURSE OBJECTIVES :
By the end of this course students will be able to:
• Read and understand journal articles relating to basic and clinical research in human disease
• Identify journal articles that pertain to written assignment questions
• Write a short concept paper that summarizes journal articles
• Be familiar with concepts relevant to the treatment of disease
• Use the breadth of topic specific knowledge from lectures and readings to both answer both fact -based
and applied questions
• Use the breadth of topic specific knowledge from lectures and readings to explain the importance of
continued research in the field
Life Sciences 2A03 and one of Biology 2BO3 or Biochemistry 2EE3.
• The lectures for modules 1 through 5 are scheduled on Tuesdays and Wednesdays at 3:30pm.
• We will also have guest lectures on various Fridays at 3:30pm that will cover topics related to medicinal
drug development and design (as indicated on the course schedule by Fri)
• Tests are scheduled as indicated on the course calendar. Any changes to this schedule will be posted on
Avenue to Learn.
This course uses Avenue to Learn to post the course outline, assignments, and other notices. Please go to
http://avenue.mcmaster.ca/ to log -on to the course’s home page.
COURSE EVALUATION :
Four term tests, 14% each, Total of 56%
Three assigned essays, 8% each: 24%
Final project 20% REQUESTS FOR RELIEF FOR MISSED ACADEMIC TERM WORK
Students may report absences lasting up to 5 days by using the McMaster Student Absence Form (MSAF) on-line,
self reporting tool, in order to request relief for missed academic work.
Students may use this tool to submit a maximum of ONE request for relief of missed academic work per term.
IMPORTANT: You must put LS3A03, as the contact ([email protected]
) on the MSAF form and immediately
after using the online tool, students MUST contact Sunita Nadella at this