LIFESCI 3K03 Lecture Notes - Lecture 18: Motor Skill, Derangement, Reciprocal Inhibition
27 Feb 2018
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Document Summary
Myoclonus = sudden jerky movements, as opposed to chorea which are more slow, dance type movements. Recruitment pattern: cranial-caudal rapid conduction near synchronous emg discharges in nearby muscles. Distribution: distal prominent in hands, feet, and face. There is a spike wave in the eeg, and a giant somatosensory evoked potential. Eeg back- averaging time-locked short latency (~30 ms for hand) cortical correlate preceding movement. Dystonia = a syndrome of sustained muscle contration, frequently causing twisting and repetitive movements, or abnormal postures (co-contraction of agonist and antagonist). It involves reduced inhibition at multiple levels: the muscles, the spinal cord, the brainstem, the cortex and the basal ganglia. We are not entirely sure what causes it but it is likely due to functional disturbance of the basal ganglia, causing altered thalamic control of cortical motor areas. The normal reciprocal innervation of opposing muscles allows for smooth muscle movements.
