LIFESCI 2N03 Lecture Notes - Lecture 13: Candela, Leptin, Reward System

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Describe the changes that occur in the brain of people who are obese. What does sugar do to the brain? why are we eating more? leptin = allows us to modulate total food intake. But now the system of leptin is broken (in obese ppl) Leptin tells brain you"ve had enough food so you can start burning energy properly. But without it, your brain thinks you"re starving. When we get more pleasure, we change our dopamine system. (dopamine: neurotransmitter that conveys feeling of pleasure) In the reward centre; when see palatable food, some parts of brain (the parts that want. But the liking part of the brain is blunted once person tasted food food) light up a lot you eat more. Person not getting more pleasure when eating, so there"s less pleasure unless. Its like living with an urge you can"t satisfy. So they have to eat more to get the same effect = tolerance.

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