LIFESCI 2N03 Lecture Notes - Lecture 47: Coronary Artery Disease, Low-Density Lipoprotein, High-Density Lipoprotein
30 Mar 2016
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Document Summary
Faty acid composiion of transporters, rbc membranes, fat stores, & muscle cells relect diet. Ldl receptors on liver crucial to circulaing ldl levels in blood; decide when to remove. Beware of low fat products (oten dairy) because subsitute energy with added carbohydrate may balance total energy so no advantage. Obesity & inacivity contribute to high ldl, low hdl cholesterol, hypertension, diabetes. Exercise increases energy expenditure and builds lean body mass reduces risk of obesity and coronary heart disease o cancer: promotes cancer once arisen; especially colon cancer. Risk associated with saturated fat (from meat) should lower in diet. Omega-3 faty acids may be protecive should increase in diet o cardiovascular disease: 5th leading cause of death; more women die than men. Atherosclerosis: hardening of arteries due to fat, cholesterol, and other substances build- up in blood vessel walls (plaque) no symptoms unil blood low to area afected.
