LIFESCI 3M03 Lecture Notes - Lecture 6: Lac Operon, Listeria Monocytogenes, Fusion Protein
3 Oct 2016
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Module 1: cells move in their local environemnts summary. Jet propulsion: requires lots of pressure and movement; whole cells can move like this; ex: aquatic organisms. Molecular motors that step along filaments: muscle contraction (actin + myosin = motor proteins); vesicle transport (microtubules) Cell crawling: linear assembly and disassembly of microfilaments (actin) macrophages ex: Hollow tube with a wall consisting of 13 protofilaments. Two intertwined chains of f- actin (noncovalent polymers of actin proteins) Eight protofilaments joined end to end with staggered overlaps. Depends on type of tissue it is present in (can identify the tissue via protein profiling) Strengthening of nerve cell axons (neurofilaments protein) Organization and maintenance of animal cell shape and polarity. Cytoplasmic streaming: movement of cytoplasm around large vacuole. Chemoattractants bind to cell surface receptors & attract cells can be internalized or stay out: cells detect soluble molecules along concentration gradients, example: amoeba attracted to the signal camp. Changes in actin (microtubules) dynamics enables cellular motility.
