MEDRADSC 1B03 Lecture Notes - Lecture 4: Viral Hepatitis, Cardiac Muscle, Skeletal Muscle

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Body knowing how to stop any of these three types of healing depends on the injury and tissues affected. Tissue returns to normal in short period of time. Replacement of injured tissue with cells of the same parenchymal type leaving little or no evidence of injury. Only when cells can go through mitosis leaving no or little injury. Ex. epithelial cells or liver cells (skin always divide, liver only when needed) Extensive damage of tissue/cells which do not regenerate (can"t go into mitosis) Replaced by connective tissue (scar/fibrous tissue- inelastic) Cells which continue to divide and replicate throughout life. Results: if injured, no or little evidence of injury. Stop dividing when growth ceases, but will regenerate if injured. If framework is present: cell will be replaced and will revert back to normal. If framework missing: cells will be replaced, but unorganized. Ex. cirrhosis of liver-fibrous bands (affects flow) Cannot regenerate, even minor injury is damaging.

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