MEDRADSC 1B03 Lecture Notes - Lecture 10: Anaplasia, Primitive Cell, Neoplasm

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Normal life span/ cycle of different cell types. Neurons: many years (do not undergo mitosis) Cancer results from altered cell growth/division and cell differentiation. Cells are specialized according to the function they perform (unspecialized to specialized) Stem cells (don"t have specialization) alter themselves into many different types of cells. New cells acquire structure and function of the cells that they replace. Irreversible alteration in adult cells leading to more primitive cell types. Something back to stem cell, increases the amount of replications taking place. Neoplasm: new formation (not a loss of specialization) Neoplasm or tumor is a cellular growth that is uncoordinated and lacks the normal regulatory controls over cell growth and division. Excessive growth deprives other cells of nutrients. Expanding mass creates pressure on surrounding structures, can throw off symmetry. Suffix usually: benign = oma; malignancy = carcinoma or sarcoma. Expanding and puts pressure on mass encapsulated.

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