MEDRADSC 2S03 Lecture Notes - Lecture 9: Benign Prostatic Hyperplasia, Gleason Grading System, Sexually Transmitted Infection
24 Jun 2016
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Document Summary
Surrounds the male urethra between the base of bladder and urogenital diaphragm. Solid organ, consists of fibrous, glandular, and muscular elements. Seminal vesicles and vas deferencs pierce the posterosuperior gland. Most common type of cancer in men. Autopsy data demonstrates disease is histologically evident in 70% of men aged. Most common in western european nations and the u. s. Diet (high fat, red meat), inactivity, smoking, alcohol, vasectomy. Chemical exposure - cadmium (pigment, corrosion-resistant plating on steel; stabilize plastic decreasing use) Bph - benign prostatic hyperplasia, sexually transmitted diseases, androgen levels (testosterone) Risk directly parallels androgen levels (highest in blacks, moderate in whites, lowest in japanese) Higher risk in 1st degree relatives (2-5 fold increased risk) Lab testing (cbc, blood chemistry psa level) Biopsy (six + core needle samples often taken) Two approaches to obtain tissue samples: o. Transrectal biopsy: needles inserted through the rectum and into prostate. Usually done in combination with trus to help guide needle o.
