MOLBIOL 3M03 Lecture 6: Guest Lecture
21 Mar 2017
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Document Summary
Dynamics of optic development: have an understanding of the tissues that interact with one another during eye development. Understand examples of how an inducer can become a responder. Induction an influencing interaction between two groups of cells or tissues. Primary induction those interactions that induce the neural tube. In amphibians, the dorsal lip cells of the blastopore induce the dorsal axis and the neural tube organizer . Inducer is tissue that produces the signal or signals that change the behaviour of the other tissues. The responder is the tissue being induced. Early optic vesicle is inducer and surface ectoderm is responder. Pax6 protein appears to be important in making the ectoderm competent to respond to the inductive signal from the optic vesicle. Once lens has formed it can induce other tissues one is optic vesicle. Ability to respond to a specific inductive signal.
