NURSING 3PA2 Lecture Notes - Lecture 3: Neonatal Sepsis, Myocardial Infarction, Sepsis

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Inflammation is an attempt by the body to eliminate injurious stimuli and promote healing. Inflammation is a non-specific reaction to stimuli such as tissue damage or infective organisms. Non-specific means that different types of insults will employ the same arsenal of protective cells and molecules. Inflammation is normally a helpful process, but sometimes it overreacts (or under-reacts, both of which can be seen in sepsis) and causes harm in clients. This issue of dysregulation of defence processes and the consequences in the conditions of sepsis, shock and pancreatitis are the subject of the following slides. The first large scale study of sepsis and its cost in the us was reported in a 2001 paper by angus and colleagues. The mortality rate was reported to be 28. 6%, although this number was lower in children and higher in the elderly. The cost at that time was an average of a little over ,000 per case, totaling . 7 billion annually nation-wide.

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