NURSING 2LA2 Lecture Notes - Lecture 1: Zona Glomerulosa, Locus Coeruleus, Allostatic Load

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Allostatic load- wear and tear from repeated or chronic stress. Hannon, chapter 9, stress and adaptation, pp. Chapter 41, disorders of endocrine control of growth and metabolism, pp. Seyle- 1956 stress response : state manifested by specific syndrome of body developed. Stressors: do(cid:374)"t (cid:374)ecessarily lead to stress response until: eustressors- positive, distress: negative, neutral- comfortable with talking to old patients unless preceptor watching. Includes external stimuli and individual judgment and physiological response stimuli plus perception leads to response: stress nonspecific response whether short or chronic cause similar responses. Stress is individual judgment conscious appraisal , demand-resource imbalance. Physiological response: people not passive victims of stressful forces- capable of change individual perception frustration anger- hormone release even anticipatory response, glucocorticoid- cortisol mineralocorticoid(aldosterone) catechola(cid:373)i(cid:374)e"s(cid:894)epi(cid:374)ephri(cid:374)e, (cid:374)or(cid:895) Adrenal glands: retroperitoneal: capsule- bulk fibrous- enclosed in fat for protection, adrenal cortex- bulk 80, zona glomerulosa- aldosterone 95% in this form (outer) Regulates na/k secretion and retention (raa pathway) Key role for volume and bp control.

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